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Riskgaming
Riskgaming
Lux Capital

A podcast by venture capital firm Lux Capital on the opportunities and risks of science, technology, finance and the human condition. Hosted... more

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Episodes

The Best of 2024

It’s been a year for the record books, and so it is with the Riskgaming podcast. We published 68 episodes... more

21 Dec 2024 · 48 minutes
Introducing our new scenario, “Powering Up”

We are really excited to announce the publication of our third and latest Riskgaming scenario, "Powering Up: China’s Global Quest... more

14 Dec 2024 · 36 minutes
Why does America have the most expensive elevators in the world?

Recently in the Riskgaming newsletter (“The Productivity Precipice”), host Danny Crichton wrote about one of the biggest challenges facing America:... more

06 Dec 2024 · 42 minutes
The Titanic Lessons of VC with Josh Wolfe

Every quarter, Lux sends an update to our limited partners observing the macroeconomic environment, the changes in venture capital, and... more

27 Nov 2024 · 30 minutes
The Orthogonal Bet: Dave Jilk on AI, Poetry, and the Future of AGI

Welcome to The Orthogonal Bet, an ongoing mini-series that explores the unconventional ideas and delightful patterns that shape our world.... more

21 Nov 2024 · 40 minutes
Elections, global threats and happy hour with the Riskgaming team

It’s not every day that we can get our distributed Riskgaming team into one podcast studio, but we actually managed... more

18 Nov 2024 · 38 minutes
The future of defense manufacturing with Anduril CEO Brian Schimpf

Anduril has become one of the most-watched companies in Silicon Valley, and for good reason. Its vertiginous rise from small... more

15 Nov 2024 · 40 minutes
The Orthogonal Bet: Embracing Second Acts with Henry Oliver⁠

Welcome to The Orthogonal Bet, an ongoing mini-series that explores the unconventional ideas and delightful patterns that shape our world.... more

14 Nov 2024 · 40 minutes
The energy economics of our civilization’s digital cathedrals

The sudden widespread usage of advanced artificial intelligence models has massively increased global demand for data centers that can handle... more

08 Nov 2024 · 44 minutes
The Orthogonal Bet: How deep science ventures redefines deep tech innovation

Welcome to The Orthogonal Bet, an ongoing mini-series that explores the unconventional ideas and delightful patterns that shape our world.... more

07 Nov 2024 · 42 minutes
Introducing our new scenario, DeepFaked and DeepSixed

We’re really excited to talk about the launch of our second public Riskgaming scenario, “DeepFaked and DeepSixed: AI Election Security... more

02 Nov 2024 · 26 minutes
The Orthogonal Bet: Exploring the history of intelligence

Welcome to The Orthogonal Bet, an ongoing mini-series that explores the unconventional ideas and delightful patterns that shape our world.... more

30 Oct 2024 · 45 minutes
Previewing our upcoming Riskgaming scenario, “Powering Up: China’s Global Quest for Electric Vehicle Dominance”

The automobile industry is one of the most pivotal in the world, both due to its scale and its nexus... more

25 Oct 2024 · 26 minutes
The Orthogonal Bet: The role of complexity in world-building

Welcome to The Orthogonal Bet, an ongoing mini-series that explores the unconventional ideas and delightful patterns that shape our world.... more

23 Oct 2024 · 38 minutes
The dangers of our rapidly narrowing understanding of China

China’s pivot from open to closed over the past decade has been striking. It wasn’t so long ago that tens... more

18 Oct 2024 · 48 minutes
The Orthogonal Bet: The Wonders of Graph Paper and Algorithmic Art

Welcome to The Orthogonal Bet, an ongoing mini-series that explores the unconventional ideas and delightful patterns that shape our world.... more

17 Oct 2024 · 44 minutes
Even with China’s rise, America’s best days are ahead

China’s vertiginous rise over the past three decades has finally dawned on the Washington DC foreign policy blob. The hopes... more

11 Oct 2024 · 44 minutes
The Orthogonal Bet: Complex economics is applying complex systems methods

Welcome to The Orthogonal Bet, an ongoing mini-series that explores the unconventional ideas and delightful patterns that shape our world.... more

09 Oct 2024 · 40 minutes
The Orthogonal Bet: Artificial Life and Robotic Evolution

Welcome to The Orthogonal Bet, an ongoing mini-series that explores the unconventional ideas and delightful patterns that shape our world.... more

02 Oct 2024 · 42 minutes
From Satellites to Submarines: The Power of Open Source Intelligence in Global Conflict

In this episode of the RISKGAMING Podcast, host Danny Crichton sits down with columnist Michael Magnani to dissect the explosive... more

01 Oct 2024 · 26 minutes
Josh Wolfe: Our new world order is one where algorithms can wield as much influence as armies

Science is the world’s greatest force for progress, but how are the people and institutions that compose this critical activity... more

27 Sep 2024 · 32 minutes
The Orthogonal Bet: From Online Communities to In-Person Programming

Welcome to The Orthogonal Bet, an ongoing mini-series that explores the unconventional ideas and delightful patterns that shape our world.... more

25 Sep 2024 · 36 minutes
The how and why of the most successful supply-chain attack in history

This week, Hezbollah fighters in Lebanon were injured and killed by the thousands across two waves of attacks when their... more

21 Sep 2024 · 48 minutes
The Orthogonal Bet: The Art of Naming

Welcome to The Orthogonal Bet, an ongoing mini-series that explores the unconventional ideas and delightful patterns that shape our world.... more

18 Sep 2024 · 30 minutes
AI is spiking chip design costs – can it solve them too?

The old adage of “If you build it, they will come” might be translated into chip design better as, “You... more

16 Sep 2024 · 26 minutes
The Orthogonal Bet: How to Navigate Complexity Within a Large Organization

Welcome to The Orthogonal Bet, an ongoing mini-series that explores the unconventional ideas and delightful patterns that shape our world.... more

12 Sep 2024 · 43 minutes
Silicon Valley’s secret industrial spy war

Silicon Valley couldn’t be farther from the confines of Langley or Fort Meade, let alone Beijing or Moscow. Yet, the... more

06 Sep 2024 · 43 minutes
The Orthogonal Bet: Bio Trajectories and the Importance of Long-Term Thinking

Welcome to The Orthogonal Bet, an ongoing mini-series that explores the unconventional ideas and delightful patterns that shape our world.... more

04 Sep 2024 · 43 minutes
How games, god(s) and chance transformed human decision-making

Gaming has enveloped our world. A majority of Americans now gamble at least once every year, and popular video games... more

30 Aug 2024 · 43 minutes
The Orthogonal Bet: The Harsh Realities of the Soviet Space Program

Welcome to The Orthogonal Bet, an ongoing mini-series that explores the unconventional ideas and delightful patterns that shape our world.... more

28 Aug 2024 · 34 minutes
The Orthogonal Bet: Understanding Embodied Intelligence

Welcome to The Orthogonal Bet, an ongoing mini-series that explores the unconventional ideas and delightful patterns that shape our world.... more

23 Aug 2024 · 44 minutes
Radical Uncertainty, Rapid Learning and the Success Equation for Catching Up

Global inequality has grown over the past two decades, concentrating an enormous amount of wealth and power on an elite... more

21 Aug 2024 · 47 minutes
The Orthogonal Bet: The Quest to Build the Fruitful Web

Welcome to The Orthogonal Bet, an ongoing mini-series that explores the unconventional ideas and delightful patterns that shape our world.... more

16 Aug 2024 · 23 minutes
Industrial literacy and the fate of American progress

It’s good and bad times in America. Inflation is down and wages are up in real terms, but there’s a... more

15 Aug 2024 · 39 minutes
The Orthogonal Bet: : The Art of Cultivating Curiosity

Welcome to The Orthogonal Bet, an ongoing mini-series that explores the unconventional ideas and delightful patterns that shape our world.... more

09 Aug 2024 · 35 minutes
Why engineers are using chaos to make computers more resilient

The CrowdStrike meltdown on July 19th shut down the world with one faulty patch — proving once again the interconnected fragility of... more

08 Aug 2024 · 34 minutes
The Orthogonal Bet: Building a Fractal Combinatorial Trope Machine

Welcome to the ongoing mini-series The Orthogonal Bet. Hosted by ⁠Samuel Arbesman⁠, a Complexity Scientist, Author, and Scientist in Residence... more

02 Aug 2024 · 45 minutes
How many trillions in damage would an invasion of Taiwan cost global GDP?

When it comes to the so-called DC foreign policy “blob”, few scenarios have been more sketched out, analyzed and wargamed... more

31 Jul 2024 · 45 minutes
The Orthogonal Bet: Using Computational Biology to Understand How the Brain Works

Welcome to the ongoing mini-series The Orthogonal Bet. Hosted by ⁠Samuel Arbesman⁠, a Complexity Scientist, Author, and Scientist in Residence... more

26 Jul 2024 · 35 minutes
Evolved Technology: Why technology is counter-intuitively pushing us back to natural products in pharma development

The history of pharmaceutical development has traditionally been one of exploration on the frontiers of life on Earth. From fungi... more

24 Jul 2024 · 21 minutes
The Orthogonal Bet: What the Microsoft Outage Reveals

Welcome to the ongoing mini-series The Orthogonal Bet. Hosted by ⁠Samuel Arbesman⁠, a Complexity Scientist, Author, and Scientist in Residence... more

19 Jul 2024 · 10 minutes
The Orthogonal Bet: The Quest to Find the Poetic Web

Welcome to the ongoing mini-series The Orthogonal Bet. Hosted by Samuel Arbesman, a Complexity Scientist, Author, and Scientist in Residence... more

19 Jul 2024 · 33 minutes
Pivoting to the Expert Economy

The media world has been rocked by artificial intelligence, labor strife, the creator economy, the decimation of business models and... more

17 Jul 2024 · 25 minutes
The Orthogonal Bet: What AI Can Learn from Human Cognition

Hello and welcome to the ongoing miniseries The Orthogonal Bet Hosted by Samuel Arbesman, Complexity Scientist, Author, and Scientist in Residence... more

12 Jul 2024 · 35 minutes
Can we be optimistic about America’s future?

If we had to rebuild American politics to be more positive, could we do it? And what would a positive... more

10 Jul 2024 · 41 minutes
The Orthogonal Bet: Unveiling the Complexity of Life: A Conversation with Philip Ball on ‘How Life Works'

Welcome to The Orthogonal Bet, an ongoing mini-series that explores the unconventional ideas and delightful patterns that shape our world. Hosted... more

05 Jul 2024 · 44 minutes
“The commons are under attack” from TikTok and subsea cables to data centers and elections

2024 is the year of democracy, with more than half of the world’s population voting in elections across India and... more

03 Jul 2024 · 38 minutes
The Orthogonal Bet: How to fund R&D that is for the public good?

In this episode, Sam speaks with Ben Reinhardt, an engineer, scientist, and the founder of a new research organization called... more

28 Jun 2024 · 26 minutes
Is AI killing journalism? Pitchforks, Perplexity and reporters yelling “Boo!”

Another week, another media tempest in a shrinking tea cup. This time, the internet’s ire centered on Perplexity AI, a... more

25 Jun 2024 · 28 minutes
The Orthogonal Bet: SimCity, Maxis and the ambitious modeling of everything

The Orthogonal Bet is an ongoing miniseries of the Riskgaming podcast that explores the unconventional ideas and delightful patterns that... more

21 Jun 2024 · 22 minutes
Why high-throughput bio research needs better tools immediately

There have been data revolutions in most areas of human activity, and biological research is no exception. The rapidly shrinking... more

14 Jun 2024 · 23 minutes
The Orthogonal Bet: Novelist Robin Sloan’s Love for Books with Maps on the First Page

Hello, and welcome to the ongoing mini-series, The Orthogonal Bet, a show that explores the unconventional ideas and delightful patterns... more

07 Jun 2024 · 42 minutes
How Applied Intuition used the Valley’s hardest lessons to upgrade automotive with autonomy

Qasar Younis and Peter Ludwig built Applied Intuition differently from most other startups. At a time of profligate spending at... more

31 May 2024 · 55 minutes
Orthogonal Bet: A technology vibe shift from utopian Star Trek to absurdist Douglas Adams?

This is the inaugural episode of an on-going mini-series for the Riskgaming podcast we’re dubbing the Orthogonal Bet. Organized by... more

24 May 2024 · 28 minutes
The soon-to-be-solved protein problem that will accelerate drug discovery

We’ve known for decades that one of the key mechanisms of biology — and of life itself — is the... more

17 May 2024 · 20 minutes
Margaret Mead and the psychedelic community that theorized AI

How does science progress? One way to look at the question is to peer into individual fields and observe the... more

03 May 2024 · 34 minutes
The nightmare specter of designer bioweapons and the people trying to stop them

Ever since the invention of CRISPR technology about a decade ago, biologists have gained increasing power to discover new DNA... more

26 Apr 2024 · 33 minutes
Lux and the Art of Startup Maintenance

Every quarter, Lux publishes our latest quarterly letter to our limited partners, highlighting the key themes we’re working on as... more

16 Apr 2024 · 24 minutes
The Zone of Totality with Sam Arbesman

This week’s solar eclipse captured the imaginations of millions of Americans throughout an arc across the continent. One of those... more

12 Apr 2024 · 9 minutes
Biology is becoming engineering and not just science

During a recent interview, Nvidia CEO Jensen Huang emphasized his interest in how Nvidia’s AI processing chips could transform the... more

15 Mar 2024 · 24 minutes
Riskgaming
The soon-to-be-solved protein problem that will accelerate drug discovery
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Description

We’ve known for decades that one of the key mechanisms of biology — and of life itself — is the binding of... more