Cole Escola has created the theater event of the year with the stunning "Oh Mary!" (moving soon to Broadway!!) and... more

This week we decide to be randomly controversial, and who better to do it with than author and critic Lauren... more

Hope you're hungry because today's episode with public intellectual, Nymphowars host, and now writer/director/star of the new film Stress Positions,... more

Do NOT call HR because Sam's real-life boss Taylor Tomlinson, superstar host of After Midnight, is off the clock and... more

Ring the Kathy Griffin alarm because the legend herself is on the podcast this week! We cover everything from catheters... more

The specter of sports and sport-like activities has haunted StraightioLab HQ for years. This week, we finally attempt a unified... more

Today's guest is writer and host of the Good One podcast Jesse David Fox. What are his qualifications? Well, he... more

Ice skating around in a little outfit? You might be thinking "sounds pretty queer"... but you'd be dead wrong. The... more

Well it's that magical time of the year when we have our dear friend Max Wittert back on the podcast... more

In one of our most intellectual episodes EVER (and that's saying a LOT), we welcome reformed Disney adult Esther Fallick... more

Welcome back to Part 2 of Earnestness Bonanza, our bi-annual call-in show where we check our world famous comedic sensibilities... more

It's time to celebrate ROMANCE with another Earnestness Bonanza, our bi-annual call-in show where we check our world famous comedic... more

This week we are joined by radical free-thinker and creator of the groundbreaking Netlfix special "Get On Your Knees" Jacqueline... more

For decades, George has been Sam's only co-worker with access to a microphone. That ends today, as we welcome Sam's... more

Pizza is one of the most powerful cultural signifiers we have, but what exactly is it signifying? This week we're... more

This week, illustrious guest Anna Seregina joins Sam in the LA studio while George is isolated in chilly New York... more

Brrrrrr...do you feel that chill? Is that the winter setting in? No! It's a DQ Blizzard being given to you... more

Hey Glamour Girls! While StraightioLab is on hiatus this week, enjoy this episode of George and Sam being guests on... more

In this country, all gay guys of age are called upon to be criminally bad trend forecasters once a year,... more

"Happy" hour? Says who, the government!? This week, we're joined by public intellectual Lauren Michele Jackson to explore the manufactured... more

Repeat after us: "Pretty girls are never on time." And yeah... "girls" is gender-neutral and "pretty" is empowering. Superstar guest... more

You've heard of three wise men, but three gay podcasters? Now THAT'S something completely unheard of...until now. That's right, the... more

This week we welcome the David Beckham of comedy (played soccer in college), the delightful Nico Carney, to talk sporting... more

Gatherers step aside because this week we have Titanique's Drew Droege on the pod to talk about hunting. Needless to... more

This week we are welcoming notable boy-daughter Karli Marulli on the podcast to clear the air on the wealthiest of... more

Today is all about hard truths, self-knowledge, reclaiming narratives, and all-fruit smoothies as we welcome to the lab one of... more

Today we're joined by the two proudly Catholic co-hosts of the Diss and Tell podcast, Matt Bellassai and Sydney Battle,... more

Everyone knows that straight people have gone as the Joker and Harley Quinn for Halloween ever since biblical times, but... more

Hootie-hoo, Bible girls! Put down that Christian rock record because boy do we have a Jesus-approved TREAT for you this... more

You know that old saying "the clothes make the man?" Well this week, Joe Pera, whose new stand-up special 'Slow... more

We all want to be a part of something! And that's bad by the way. Today we're joined by crossword... more

The first day of school comes but once a year, but the ramifacations of your outfit...well they can be felt... more

If you're on Letterboxd... do NOT read this! Today we're joined by the delightful Bridger Winegar, host of "I Said... more

As many of you know we have been on the most groundbreaking tour of the summer (better luck next time... more

Are we in a Peloton class, because our heart rates are UP this week as we go full talk show... more

Hootie-hoo, glamour girls! Welcome back to the lab after a lovely, lazy, Labor Day weekend. We can't believe the FOURTH... more

Lunch. Such a common meal and yet...what do we really know about it? Can anyone define it? Why hasn't the... more

This week we're revisiting an old favorite featuring the legendary, one and only Meg Stalter! This episode was originally recorded... more

This week we welcome 'Lovett or Leave It' host Jon Lovett to the lab for a string of explosive revelations,... more

This week we are saying "hello" or potentially even "bonjour" (if it isn't too culturally insensitive) from our live show... more

This week we're joined in the studio by bisexual SAG member and proud returning guest Mary Beth Barone, who keeps... more

Today we are coming at you in complete accordance with strike rules by having the illustrious Liza Treyger on the... more

You've read the title of this episode, and you're already furious. "AUNTIES?!" you scream. "They are NOT straight!!" Well first... more

This week we're releasing our June live show from The Bell House in Brooklyn. Previously a patreon exclusive, we've decided... more

It's time for our biannual Earnestness Bonanza, where we DROP THE ACT and answer listener questions as earnestly as possible.... more

Today we at StraightioLab Inc. are thrilled to celebrate Pride by presenting a special, potentially once-in-a-lifetime episode of our sister... more

The rumors are true: We're taking our famous StraightioLab live show on the road! If you're a glamour-identified individual within... more

StraightioLab All-Star Amy Zimmer returns to the hot seat along with her introverted friend "Kelly" for an episode that defies... more

This week our disgusting little podcast is classed up by someone who finally understands the power of showbiz: Peter Smith.... more

Sorry, what was that? We couldn't hear you because we were reading the New York Times bestselling book RAW DOG... more

Today we are joined by Sam Sanders, the host of Into It and Vibe Check, to discuss the most intersectional... more

Today we are joined once again by StraightioLab favorite and Sam's sexy Los Angeles-based stepmother Greta Titelman to finally talk... more

This week we invite the unironically illustrious Aparna Nancherla on to shift our perspectives on many of the leading issues... more

This week we are defiantly going GUEST-LESS to discuss the wall-to-wall elephant in the room: carpets. We walk on them,... more

This week, we are joined by StraightioLab darling Sydnee Washington who takes us on a roller coaster ride of intellectual... more

Today we are joined by our illustrious podcasting sisters Rose Dommu and Fran Tirado of the Like a Virgin podcast... more

This week we have the honor and privelage of being just a little rude to our dear friend Chris Murphy.... more

Former vice president of her Miami-based gay-straight alliance Milly Tamarez joins Sam and George to start some difficult conversations about... more

Today we have comedian, writer, and boutique sweater designer Maeve "Mohair" Higgins on the podcast to talk about green card... more

Grand Marshal of the StraightioLab Pride Parade Alison Roman finally joins us this week just in time for the release... more