Today we're thrilled to have Catherine Cohen on to help us break the seal of yet another national tragedy. No... more

Recorded two days after the election, this episode is raw, real, and occasionally incoherent in ways few other podcasts would... more

Today we are joined by nightlife legend and general encyclopedia Charlene Incarnate to talk about theater. That's right, theater is... more

Forget everything you know, because today's episode with the one and only Martine (Fantasmas, Los Espookys) takes every existing paradigm,... more

Today we're joined by Stavros Halkias whose new movie "Let's Start A Cult" is out October 25th. We discuss the... more

In honor of National Coming Out Day, please enjoy this bonus episode of StraightioLab presented by Chase Freedom and The... more

We're all familiar with the classic American flag, which celebrates values like freedom, Big Gulps, and flawless foreign policy. But... more

It's time for part two of our Earnestness Bonanza where we DROP THE ACT and answer listener questions HONESTLY. This... more

It's time for Earnestness Bonanza, our bi-annual call-in show where we DROP THE ACT and answer listener questions HONESTLY. This... more

Today is a red letter day at Straighio HQ for two reasons. First is that we got to have the... more

It was... SASHEER all along?! This week we're joined once again by our dear friend Sasheer Zamata, star of Marvel's... more

Can watching a movie make you smart? No. But it can trick you into feeling smart and that's the magic... more

Hootie-hoo, glamour girls! It's Season 5 now, or 4? No one knows for sure, but we're glad to be back!... more

Hootie-hoo, glamour girls! StraightioLab will be on hiatus for August. Please enjoy this re-release episode with Maeve Higgins! -- Today... more

Hootie-hoo, glamour girls! StraightioLab will be on hiatus for August. Please enjoy this re-release episode with Sabrina Wu!  --- In... more

Hootie-hoo, glamour girls! StraightioLab will be on hiatus for August. Please enjoy this PATREON episode with the infamous, Max Wittert. ... more

Hootie-hoo, glamour girls! StraightioLab will be on hiatus for August. Please enjoy this classic GAYTIOLAB episode with Macy Rodman! MERCH... more

Finally, we talk about what's gay and what's straight. Finally! **StraightioLab will be taking a hiatus in August, but please... more

Paging Doctor Freud! And wait, WHO is that again? Today, along with the hilarious and wise EJ Marcus, we use... more

Hey, StraightioLab listeners! We wanted to share a really fun new show we think you'll love, Sniffies Cruising Confessions from... more

Hope you're ready to learn a thing or two because this week we have Kate Willett on to talk incel... more

Today we are joined by our dear friend Mo Fry Pasic (catch her play WORSE THAN YOU at Edinburgh Fringe... more

This week we're un-paywalling our recent Patreon ep "The Things Of Summer." We explore everything trending this summer from the... more

Today we go back to our combative and abrasive roots with reptile expert and comedian Vinny Thomas. We talk about... more

And today we have a case of the GIGGLES as we're joined by the hilarious hosts of the brand-new podcast... more

It's officially Pride Month and that means it's time for our world famous special edition podcast: GaytioLab! And who better... more

We've all "voted" before, but to what end? Today we are joined by our dear friend Clare O'Kane to explore... more

Today we welcome back comedian, visionary, and water-on-laptop survivor Brittany Carney to talk about butts. That's right. Butts. Of course,... more

Rent the Runway? Don't mind if I do! Or do I? Bicoastal beauty Courtney O'Donnell joins us to chat about... more

StraightioLab has always been about pushing the boundaries of podcasting and this episode finds us once again completely reinventing the... more

It's time to POP the collars of your layered pastel polos and welcome our dear friend Hannah Pilkes to the... more

Cole Escola has created the theater event of the year with the stunning "Oh Mary!" (moving soon to Broadway!!) and... more

This week we decide to be randomly controversial, and who better to do it with than author and critic Lauren... more

Hope you're hungry because today's episode with public intellectual, Nymphowars host, and now writer/director/star of the new film Stress Positions,... more

Do NOT call HR because Sam's real-life boss Taylor Tomlinson, superstar host of After Midnight, is off the clock and... more

Ring the Kathy Griffin alarm because the legend herself is on the podcast this week! We cover everything from catheters... more

The specter of sports and sport-like activities has haunted StraightioLab HQ for years. This week, we finally attempt a unified... more

Today's guest is writer and host of the Good One podcast Jesse David Fox. What are his qualifications? Well, he... more

Ice skating around in a little outfit? You might be thinking "sounds pretty queer"... but you'd be dead wrong. The... more

Well it's that magical time of the year when we have our dear friend Max Wittert back on the podcast... more

In one of our most intellectual episodes EVER (and that's saying a LOT), we welcome reformed Disney adult Esther Fallick... more

Welcome back to Part 2 of Earnestness Bonanza, our bi-annual call-in show where we check our world famous comedic sensibilities... more

It's time to celebrate ROMANCE with another Earnestness Bonanza, our bi-annual call-in show where we check our world famous comedic... more

This week we are joined by radical free-thinker and creator of the groundbreaking Netlfix special "Get On Your Knees" Jacqueline... more

For decades, George has been Sam's only co-worker with access to a microphone. That ends today, as we welcome Sam's... more

Pizza is one of the most powerful cultural signifiers we have, but what exactly is it signifying? This week we're... more

This week, illustrious guest Anna Seregina joins Sam in the LA studio while George is isolated in chilly New York... more

Brrrrrr...do you feel that chill? Is that the winter setting in? No! It's a DQ Blizzard being given to you... more

Hey Glamour Girls! While StraightioLab is on hiatus this week, enjoy this episode of George and Sam being guests on... more

In this country, all gay guys of age are called upon to be criminally bad trend forecasters once a year,... more

"Happy" hour? Says who, the government!? This week, we're joined by public intellectual Lauren Michele Jackson to explore the manufactured... more

Repeat after us: "Pretty girls are never on time." And yeah... "girls" is gender-neutral and "pretty" is empowering. Superstar guest... more

You've heard of three wise men, but three gay podcasters? Now THAT'S something completely unheard of...until now. That's right, the... more

This week we welcome the David Beckham of comedy (played soccer in college), the delightful Nico Carney, to talk sporting... more

Gatherers step aside because this week we have Titanique's Drew Droege on the pod to talk about hunting. Needless to... more

This week we are welcoming notable boy-daughter Karli Marulli on the podcast to clear the air on the wealthiest of... more

Today is all about hard truths, self-knowledge, reclaiming narratives, and all-fruit smoothies as we welcome to the lab one of... more

Today we're joined by the two proudly Catholic co-hosts of the Diss and Tell podcast, Matt Bellassai and Sydney Battle,... more

Everyone knows that straight people have gone as the Joker and Harley Quinn for Halloween ever since biblical times, but... more

Hootie-hoo, Bible girls! Put down that Christian rock record because boy do we have a Jesus-approved TREAT for you this... more