It's time to POP the collars of your layered pastel polos and welcome our dear friend Hannah Pilkes to the... more

Cole Escola has created the theater event of the year with the stunning "Oh Mary!" (moving soon to Broadway!!) and... more

This week we decide to be randomly controversial, and who better to do it with than author and critic Lauren... more

Hope you're hungry because today's episode with public intellectual, Nymphowars host, and now writer/director/star of the new film Stress Positions,... more

Do NOT call HR because Sam's real-life boss Taylor Tomlinson, superstar host of After Midnight, is off the clock and... more

Ring the Kathy Griffin alarm because the legend herself is on the podcast this week! We cover everything from catheters... more

The specter of sports and sport-like activities has haunted StraightioLab HQ for years. This week, we finally attempt a unified... more

Today's guest is writer and host of the Good One podcast Jesse David Fox. What are his qualifications? Well, he... more

Ice skating around in a little outfit? You might be thinking "sounds pretty queer"... but you'd be dead wrong. The... more

Well it's that magical time of the year when we have our dear friend Max Wittert back on the podcast... more

In one of our most intellectual episodes EVER (and that's saying a LOT), we welcome reformed Disney adult Esther Fallick... more

Welcome back to Part 2 of Earnestness Bonanza, our bi-annual call-in show where we check our world famous comedic sensibilities... more

It's time to celebrate ROMANCE with another Earnestness Bonanza, our bi-annual call-in show where we check our world famous comedic... more

This week we are joined by radical free-thinker and creator of the groundbreaking Netlfix special "Get On Your Knees" Jacqueline... more

For decades, George has been Sam's only co-worker with access to a microphone. That ends today, as we welcome Sam's... more

Pizza is one of the most powerful cultural signifiers we have, but what exactly is it signifying? This week we're... more

This week, illustrious guest Anna Seregina joins Sam in the LA studio while George is isolated in chilly New York... more

Brrrrrr...do you feel that chill? Is that the winter setting in? No! It's a DQ Blizzard being given to you... more

Hey Glamour Girls! While StraightioLab is on hiatus this week, enjoy this episode of George and Sam being guests on... more

In this country, all gay guys of age are called upon to be criminally bad trend forecasters once a year,... more

"Happy" hour? Says who, the government!? This week, we're joined by public intellectual Lauren Michele Jackson to explore the manufactured... more

Repeat after us: "Pretty girls are never on time." And yeah... "girls" is gender-neutral and "pretty" is empowering. Superstar guest... more

You've heard of three wise men, but three gay podcasters? Now THAT'S something completely unheard of...until now. That's right, the... more

This week we welcome the David Beckham of comedy (played soccer in college), the delightful Nico Carney, to talk sporting... more

Gatherers step aside because this week we have Titanique's Drew Droege on the pod to talk about hunting. Needless to... more

This week we are welcoming notable boy-daughter Karli Marulli on the podcast to clear the air on the wealthiest of... more

Today is all about hard truths, self-knowledge, reclaiming narratives, and all-fruit smoothies as we welcome to the lab one of... more

Today we're joined by the two proudly Catholic co-hosts of the Diss and Tell podcast, Matt Bellassai and Sydney Battle,... more

Everyone knows that straight people have gone as the Joker and Harley Quinn for Halloween ever since biblical times, but... more

Hootie-hoo, Bible girls! Put down that Christian rock record because boy do we have a Jesus-approved TREAT for you this... more